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International Cancer Genome Consortium : ウィキペディア英語版
International Cancer Genome Consortium
The International Cancer Genome Consortium (ICGC) is a voluntary scientific organization that provides a forum for collaboration among the world's leading cancer and genomic researchers. The ICGC was launched in 2008 to coordinate large-scale cancer genome studies in tumours from 50 cancer types and/or subtypes that are of main importance across the globe.
Systematic studies of more than 25,000 cancer genomes at the genomic, epigenomic and transcriptomic levels will reveal the repertoire of oncogenic mutations, uncover traces of the mutagenic influences, define clinically relevant subtypes for prognosis and therapeutic management, and enable the development of new cancer therapies.
==Structure and funding==

ICGC is funded by participating nations, each of which focuses on one or more forms of cancer, with the goal of mapping the genomes of at least 50 types of cancer. The consortium's secretariat is at the Ontario Institute for Cancer Research in Toronto, Canada, which will also operate the data coordination center. The provincial Government of Ontario provided funding of $40 million, and each participating funding member is expected to contribute $20 million toward each project. In 2009 the German Cancer Aid supported one ICGC-project with 7.9 million Euro. This was the highest amount a private organization gave. The money is donated by German people.
ICGC membership is open to all entities that agree to follow its principles and guidelines. The ICGC has received commitments from funding organizations in Asia, Australia, Europe and North America for 47 project teams in 15 jurisdictions to study over 21,000 tumor genomes. Projects that are currently funded are examining tumors affecting the bladder, blood, bone, brain, breast, cervix, colon, head and neck, kidney, liver, lung, oral cavity, ovary, pancreas, prostate, rectum, skin, soft tissues, stomach, thyroid and uterus. Over time, additional nations and organizations are anticipated to join the ICGC. The genomic analyses of tumors conducted by ICGC members in Australia and Canada (pancreatic cancer), China (gastric cancer), France (liver cancer), Germany (brain cancer), Japan (liver cancer), Spain (blood cancer), the UK (blood, breast, lung and skin cancer) and the USA (blood, brain, breast, colon, kidney, lung, ovarian, rectal, stomach and uterine cancer) are now available through the Data Coordination Center housed on the ICGC website at www.icgc.org.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「International Cancer Genome Consortium」の詳細全文を読む



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